SynGAP Research Fund Grant Application

The SynGAP Research Fund’s grant program awards one-year research grants up to $65,000 and two-year grants up to $130,0000 to young investigators, laboratory-based researchers and clinicians who are interested in studying SYNGAP1 Encephalopathy. 

Our grants are intended to help researchers explore novel ideas and answer questions related to the clinical aspects, therapies and/or genetic causes of SYNGAP1. Grant recipients are asked to give a presentation at SynGAP Research Fund’s research roundtable at the American Epilepsy Society the following year to discuss their work. 

Full grant applications are reviewed twice a year by SRF’s Scientific Advisory Board (SAB) and must be submitted by March 1 or September 1 to be included in the early/late review cycles, respectively. 

Note: SRF has a Board-directed policy that does not allow for the payment of indirect costs to nonprofit institutions.

Please follow the instructions below to submit either a letter of intent or full application for a grant.

Application Guidelines

A full application packet must be received by the deadline specified above for the SAB to review and approve a grant. If you would like your idea to be reviewed by our medical science team prior to drafting a full application, please submit a letter of intent (LOI) and our team will contact you for a follow-up discussion.

Please submit all documents or any questions to and a team member will promptly get in touch.

Letter of Intent (LOI) Requirements

LOI must clearly outline hypothesis and aims and include a description of how research will benefit patients with SYNGAP1 Encephalopathy, along with an estimated budget range. Maximum 2 pages.

Full Application Requirements

  • Title Page: Provide the proposal title and PI information
  • Abstract: Provide a lay summary and a scientific summary of the project
  • Budget: Provide a detailed budget and justification, including existing sources of funding the PI(s) are currently receiving
  • Proposal (NIH format is acceptable but not required)
  • Biosketch for each PI
  • Letters of support or collaboration as relevant

Thank you for your interest in advancing SYNGAP1 research and helping patients around the world.